Impact of Vaccination in Humans


 * Prior IV vaccination was associated with less severe clinical course and improved overall long-term survival in patients with CAP during IV seasons (TESSMER et al., 2011).
 * Within the off-season cohort there was no significant influence of vaccination status on community acquired pneumonia severity or disease outcome (TESSMER et al., 2011).
 * The study suggests that prior IV vaccination is associated with a less severe course of community acquired pneumonia during the IV season and improved long-term survival (TESSMER et al., 2011).
 * On people aged 65 years or older, the incidence of hospital treatment was lower in the vaccinated than in the unvaccinated cohort (IV and SP vaccination with trivalent, split-virion, IV vaccine and 23-valent, SP polysaccharide vaccine). The total mortality was 57% lower in vaccinated than in unvaccinated individuals (CHRISTENSON et al., 2001).